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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN1
All Species:
17.88
Human Site:
T388
Identified Species:
30.26
UniProt:
Q16512
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16512
NP_002732.3
942
103932
T388
L
K
A
E
A
E
N
T
S
E
V
S
T
V
L
Chimpanzee
Pan troglodytes
XP_512443
1169
127241
T615
L
K
A
E
A
E
N
T
S
E
V
S
T
V
L
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
Q456
V
D
N
R
V
V
G
Q
T
G
W
G
Q
V
A
Dog
Lupus familis
XP_542019
1076
118222
T521
L
K
V
E
A
E
N
T
S
E
V
S
T
V
L
Cat
Felis silvestris
Mouse
Mus musculus
P70268
946
104392
A391
L
R
G
E
A
E
N
A
T
E
V
S
T
V
L
Rat
Rattus norvegicus
Q63433
946
104449
S391
L
K
G
E
A
E
N
S
T
E
V
S
T
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
Q443
V
D
N
R
V
V
G
Q
T
G
W
G
P
V
S
Chicken
Gallus gallus
XP_422357
1013
114806
S416
L
L
K
T
D
D
L
S
N
E
V
C
A
V
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689331
948
107057
S401
P
L
K
T
D
E
L
S
S
D
V
S
A
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
C163
R
F
T
F
C
D
H
C
G
S
L
L
Y
G
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
Q236
E
E
L
G
K
E
I
Q
E
T
G
A
G
R
F
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
E295
M
C
L
N
L
E
P
E
G
L
L
F
T
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
E354
S
A
K
N
V
Q
G
E
N
T
S
T
S
Q
I
Red Bread Mold
Neurospora crassa
P87253
1142
127954
K442
G
M
D
R
L
G
R
K
G
A
V
R
Q
R
K
Conservation
Percent
Protein Identity:
100
79.3
38.7
83
N.A.
91.6
91.9
N.A.
42.2
57.6
N.A.
66.7
N.A.
29
N.A.
27.8
48.5
Protein Similarity:
100
79.9
52.6
84.3
N.A.
94.7
94.6
N.A.
56.1
72.1
N.A.
79.5
N.A.
42.8
N.A.
43.4
61.7
P-Site Identity:
100
100
6.6
93.3
N.A.
73.3
80
N.A.
6.6
33.3
N.A.
40
N.A.
6.6
N.A.
6.6
13.3
P-Site Similarity:
100
100
20
93.3
N.A.
86.6
93.3
N.A.
20
53.3
N.A.
53.3
N.A.
26.6
N.A.
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.8
28.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.4
45.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
15
0
36
0
0
8
0
8
0
8
15
0
8
% A
% Cys:
0
8
0
0
8
0
0
8
0
0
0
8
0
0
0
% C
% Asp:
0
15
8
0
15
15
0
0
0
8
0
0
0
0
0
% D
% Glu:
8
8
0
36
0
58
0
15
8
43
0
0
0
8
0
% E
% Phe:
0
8
0
8
0
0
0
0
0
0
0
8
0
0
8
% F
% Gly:
8
0
15
8
0
8
22
0
22
15
8
15
8
8
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
15
% I
% Lys:
0
29
22
0
8
0
0
8
0
0
0
0
0
0
8
% K
% Leu:
43
15
15
0
15
0
15
0
0
8
15
8
0
0
58
% L
% Met:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
15
15
0
0
36
0
15
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
8
0
22
0
0
0
0
15
8
0
% Q
% Arg:
8
8
0
22
0
0
8
0
0
0
0
8
0
15
0
% R
% Ser:
8
0
0
0
0
0
0
22
29
8
8
43
8
0
8
% S
% Thr:
0
0
8
15
0
0
0
22
29
15
0
8
43
0
0
% T
% Val:
15
0
8
0
22
15
0
0
0
0
58
0
0
65
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _